Publications

Contributions to books

Ersfeld, K.
Fluorescence in situ hybridization on stretched DNA (Fibre-FISH). In: Methods in Molecular Biology: Parasite Genomics Protocols (ed. S. Melville), Humana Press, USA, 2004.

Ersfeld, K. and Stone, E.
The simultaneous detection of proteins and DNA in cells. In: Protein Localization by Fluorescence Microscopy: A Practical Approach. (ed. V. Allan), Oxford University Press, 1999, pp 51-66.

Research papers

Jentzsch, J., Sabri, A., Speckner, K., Lallinger-Kube, G., Weiss, M., Ersfeld, K.
Microtubule polyglutamylation is important for regulating cytoskeletal architecture in Trypanosoma brucei.
Journal of Cell Science, doi 10.1242/jcs.248047 (2020)

Koko, W., Jentzsch, J., Kalie, H., Schobert, R., Ersfeld, K., Al Nasr, I., Khan, T., Biersack, B.
Evaluation of the antiparasitic activities of imidazol-2-ylidene-gold(I) complexes
​Archiv der Pharmazie, e1900363 (2020)

Jentzsch, J., Koko, W., Al Nasr, I., Khan, T., Schobert, R., Ersfeld, K. Biersack, B.
New antiparasitic bis-naphtoquinone derivatives.
Chem Biodiversity, Vol. 17, e1900597 (2020)

Al Nasr, I., Jentzsch, J. Winter. I., Schobert, R., Ersfeld, K., Koko, W., Mujawah, A., Khan, T. Biersack, B.
Antiparasitic activities of new lawsone Mannich bases.
Archiv der Pharmazie, Vol. 352, e1900128 (2019)

Winter, I., Lockhauserbäumer, J., Lallinger-Kube, G., Schobert, R., Ersfeld, K., Biersack, B.
Anti-trypanosomal activity of cationic N-heterocyclic carbene gold(I) complexes.
Molecular and Biochemical Parasitology, Vol. 214, 112-120 (2017)

Mahal, K. Ahmad, A. Schmitt, F., Lockhauserbäumer, J., Starz, K., Pradhan, R., Padhye, S., Sarkar, F.H., Koko, W.S., Schobert, R. Ersfeld, K., Biersack, B.
Improved anticancer and antiparasitic activity of new lawsone Mannich bases.
European Journal of Medicinal Chemistry, Vol. 126, 421-431 (2017)

Narayanan, M. S., Kushwaha, M., Ersfeld, K. Fullbrook, A., Stanne, T. M., Rudenko, G.
NLP is a novel nucleoplasmin-like protein involved in in VSG expression site control in Trypanosoma brucei.
Nucleic Acids Research, Vol 39, 2018-31 (2011)

Kuan Yoow, C. and Ersfeld, K.
The role of the Kinesin-13 family protein TbKif13-2 in flagellar length regulation of Trypanosoma brucei
Molecular and Biochemical Parasitology, Vol 174, 137-140 (2010)

Kuan Yoow, C., Matthews, K., Ersfeld, K.
Functional characterisation and drug target validation of a mitotic Kinesin-13 in Trypanosoma brucei.
PLoS Pathogens, Vol. 6, e1001050 (2010)

Denninger, V., Fullbrook, A., Bessat, M., Ersfeld, K., Rudenko, G.
The FACT subunit TbSpt16 is involved in cell cycle specific control of VSG expression sites in Trypanosoma brucei.
Molecular Microbiology, Vol. 78, 459-474 (2010)

Liu, W., Apagayi, K. McLeavy, L., Ersfeld, K.
Expression and cellular localisation of calpain-like proteins in Trypanosoma brucei.
Molecular and Biochemical Parasitology, Vol 169, 20-26 (2010)

Patrick, K., Shi, H., Kolev, N., Ersfeld, K., Tschudi, C., Ullu, E.
Distinct and overlapping roles for two Dicer-like proteins in the RNA interference pathways of the ancient eukaryote Trypanosoma brucei.
Proceedings of the National Academy of Sciences, USA (PNAS), Vol 106, 17933-17938 (2009)

Bessat, M and Ersfeld, K.
Functional characterisation of cohesin SMC3 and separase and their roles in the segregation of large and minichromosomes in Trypanosoma brucei.
Molecular Microbiology, Vol 71, 1371-1385 (2009)

Durand-Dubief, M., Absalon, S., Menzer, L., Ngwabyt, S., Ersfeld, K., Bastin, P.
The argonaute protein TbAGO1 contributes to large and mini-chromosome segregation and is required for control of RIME retroposons and RHS pseudogene-associated transcripts.
Molecular and Biochemical Parasitology, Vol 156, 144-153 (2007)

Hughes, K., Wand, M., Foulston, L., Young, R., Harley, K. Terry, S. Ersfeld, K., Rudenko, G.
A novel ISWI is involved in VSG expression site downregulation in African trypanosomes.
EMBO Journal, Vol. 26, 2400-2410 (2007)

Kelly, S. Singleton, W, Wickstead, B, Ersfeld, K. Gull, K.
Characterisation and differential nuclear localisation of Nopp140 and a novel Nopp140 like protein in trypanosomes.
Eukaryotic Cell, Vol. 5, 876-879 (2006)

Meyer, S., Barber, L.M., White, D.J., Will, A.M., Birch, J.M., Kohler, J., Ersfeld, K., Bloom, E., Eden, T.O.B., Taylor, G.M.
Spectrum and Significance of Variants and Mutations in the Fanconi Anaemia Group G Gene (FANCG) in Children with Sporadic Acute Myeloid Leukaemia.
British Journal of Haematology, Vol. 133, 284-292 (2006)

Ersfeld, K., Barraclough, H., Gull, K.
Evolutionary relationships and protein domain architecture in an expanded calpain superfamily in kinetoplastid parasites.
Journal of Molecular Evolution Vol. 61, 742-757 (2005)

Wickstead, B., Ersfeld, K., Gull, K.
The small chromosomes of Trypanosoma brucei involved in antigenic variation are constructed around repetitive palindromes.
Genome Research, Vol. 14, 1014-1024 (2004)

Wickstead, B., Ersfeld, K., Gull, K.
The mitotic stability of minichromosomes of Trypanosoma brucei.
Molecular and Biochemical Parasitology, Vol. 132, 97-100 (2003)

Wickstead, B., Ersfeld, K., Gull, K.
The frequency of gene targeting in Trypanosoma brucei is independent of target site copy numbers.
Nucleic Acids Research, Vol. 31, 1-8 (2003) [IF 6.9]

Alsford, N.S, Navarro, M., Jamnadass, H.R, Dunbar, H.E., Ackroyd, M.R., Murphy, N. , Gull, K., Ersfeld, K.
The identification of circular extrachromosomal DNA in the nuclear genome of Trypanosoma brucei.
Molecular Microbiology, Vol. 47, 277-289 (2003)

Wickstead, B., Ersfeld, K., Gull, K.
Targeting of a tetracyclin-inducible expression system to the transcriptionally silent minichromosomes of Trypanosoma brucei.
Molecular and Biochemical Parasitology, Vol. 125, 211-216 (2002)

Hertz-Fowler, C., Ersfeld, K., Gull, K.
CAP 5.5, a life cycle regulated, cytoskeleton-associated-protein is a member of a novel family of calpain-related proteins inTrypanosoma brucei.
Molecular and Biochemical Parasitology, Vol. 116, 25-34 (2001)

Alsford, S. N., Wickstead, B., Ersfeld, K., Gull, K.
Diversity and dynamics of the minichromosomal karyotype in Trypanosoma brucei
Molecular and Biochemical Parasitology, Vol. 113, 79-88 (2001)

Ersfeld, K., Gull, K.
Targeting of cytoskeletal proteins to the flagellum of Trypanosoma brucei.
Journal of Cell Science, Vol. 114, 141-148 (2000)

Ogbadoyi, E., Ersfeld, K., Robinson, D., Sherwin, T., Gull, K.
The architecture of the Trypanosoma brucei nucleus during interphase and mitosis.
Chromosoma, Vol. 108, 501-513 (2000)

Clayton, C. et al.
Genetic nomenclature for Trypanosoma and Leishmania.
Molecular and Biochemical Parasitology, Vol. 97, 221-224 (1998)

Ersfeld, K., Asbeck, K., Gull, K.
Direct visualisation of gene organisation in Trypanosoma brucei by high-resolution in situ hybridisation.
Chromosoma, Vol. 107, 237-240 (1998)

Ersfeld, K. Gull, K.
Partitioning of large and minichromosomes in Trypanosoma brucei.
Science, Vol. 276, 611-614 (1997)

McVie, A., Ersfeld, K., Rogan, M. T., Craig, P.S.:
Expression and immunological characterisation of Echinococcus granulosus. recombinant antigen B for IgG4 subclass detection in human cystic echinococcosis.
Acta Tropica, Vol. 67, 19-35 (1997)

Ambrosio, J., Cruz, M., Allan, J., Moran, E., Ersfeld, K., Flisser, A.
Identification and partial characterisation of a myosin-like protein from cysticerci and adults of Taenia solium using a monoclonal antibody.
Parasitology, Vol. 114, 545-553 (1997)

Ibrahem, M. M., Craig, P. S., McVie, A., Ersfeld, K., Rogan, M. T.
Echinococcus granulosus antigen B and seroreactivity in natural ovine hydatidosis.
Research in Veterinary Science, Vol. 61, 102-106 (1996)

Ersfeld, K., Gasser, R., Craig, P.S.:
The immunodiagnostic potential of Echinococcus granulosus adult stage antigens in human echinococcosis.
Parasitology Research, Vol. 83, 90-92 (1996)

Ersfeld, K., Docherty, R., Alsford, S., Gull, K.
A fluorescence in situ hybridisation study of the regulation of histone mRNA levels during the cell cycle of Trypanosoma brucei.
Molecular and Biochemical Parasitology, Vol. 81, 201-209 (1996)

Ersfeld, K. and P. S. Craig:
Cloning and immunological characterisation of Echinococcus granulosus ferritin.
Parasitology Research, Vol. 81, 382-387 (1995)

Patakh, K.M.L., Allan, J.C., Ersfeld, K., Craig, P.S.:
A Western blot and ELISA assay for the diagnosis of porcine cysticercosis.
Veterinary Parasitology, Vol. 53, 209-217 (1994)

Ersfeld, K., Wehland, J., Plessmann, U., Dodemont, H., Gerke, V., Weber, K.:
Characterization of the Tubulin-Tyrosine Ligase.
Journal of Cell Biology, Vol.120, 725-732 (1993)

Reviews

Ersfeld, K.
Nuclear architecture, genome and chromatin organisation in Trypanosoma brucei.
Research in Microbiology, Vol. 162, 626-636 (2011)

Croall, D.E., Ersfeld, K.
The calpains: Modular designs and functional diversity
Genome Biology, Vol.8, 218 (2007)

Ersfeld, K.
Genome projects of parasitic protozoa.
Current Issues in Molecular Biology, Vol. 5, 61-74 (2003)

Wickstead, B, Ersfeld, K., Gull, K.
Repetitive elements in genomes of parasitic protozoa.
Microbiology and Molecular Biology Reviews, Vol. 67, 360-375 (2003)

Ersfeld, K., Melville, S., Gull, K.
Nuclear and genome organisation in Trypanosoma brucei.
Parasitology Today, Vol. 15, 58-63 (1999)

Gull, K., Alsford, S., Ersfeld, K.
The segregation of small chromosomes in eukaryotes.
Trends in Microbiology, Vol. 6, 319-323 (1998)